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Nodal modulator 1 (pM5, NOMO1, PM5)
Function:
- may antagonize Nodal signaling
Compartment: membrane
Expression:
- expressed in colon tumor tissue & in adjacent normal colonic mucosa, 1.5-fold more in normal colonic mucosa than in colon tumor tissue (at protein level)
Genetics:
- there are 3 copies of the NOMO gene on chromosome 16p12-p13: NOMO1, NOMO2 (AC Q5JPE7) and NOMO3 (AC P69849)
- all 3 very similar
Related
nodal homolog (NODAL)
nodal modulator
General
glycoprotein
membrane protein
Properties
SIZE: MW = 134 kD
entity length = 1222 aa
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-31}
N-glycosylation site {N50}
N-glycosylation site {N218}
N-glycosylation site {N618}
transmembrane domain {1156-1176}
Database Correlations
UniProt Q15155
Pfam PF05738
References
UniProt :accession Q15155