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nociceptive pain
Etiology:
- somatic: tissue injury: bones, soft tissue, joints, muscle
- visceral: renal colic, constipation [1]
Pathology:
- pain transmission (nociception)
- usually relating to a receptive neuron (nociceptin receptor) for painful sensations
Clinical manifestations:
- somatic:
- localized to site of tissue injury
- dull, aching or throbbing pain
- visceral:
- diffuse, poorly localized, referred to other sites
- intermittent, paroxysmal
- dull, colicky, squeezing, deep, cramping
- often with nausea, vomiting, diaphoresis [2]
Management:
- somatic
- physical therapy
- cognitive behavioral therapy
- acetaminophen, NSAIDs, opiates [2]
- visceral
- treatment of underlying cause
- physical therapy
- cognitive behavioral therapy
- acetaminophen, opiates [2]
Related
nociceptin ([Contains: Neuropeptide 1; Nociceptin (Orphanin FQ) (PPNOC); Neuropeptide 2], PNOC, OFQ)
nociceptin receptor; orphanin FQ receptor; kappa-type 3 opioid receptor; KOR-3 (OPRL1 OOR ORL1)
nociception
nociceptor
General
pain [odyn-]
References
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
- Geriatric Review Syllabus, 11th edition (GRS11)
Harper GM, Lyons WL, Potter JF (eds)
American Geriatrics Society, 2022