NHP2-like protein 1 (high mobility group-like nuclear protein 2 homolog 1, U4/U6.U5 tri-snRNP 15.5 kD protein, OTK27, hSNU13, sperm-specific antigen 1, SSFA1, NHP2L1)

Function: 1) binds to the 5' stem-loop of U4 snRNA 2) role in the late stage of spliceosome assembly (putative) 3) conformational change upon RNA-binding 4) interacts with RAD17 Compartment: - nucleus, nucleolus - concentrated in dense fibrillar component of nucleolus Expression: ubiquitous

General

nuclear protein RNA-binding protein

Properties

SIZE: MW = 14 kD entity length = 127 aa COMPARTMENT: cell nucleus MOTIF: acetylation site SITE: 1-1 EFFECTOR-BOUND: acetyl

Database Correlations

OMIM correlations UniProt P55769 Pfam PF01248

References

UniProt :accession P55769