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NF kappa B responsive genes
Genes regulated by NF kappa B include cell adhesion molecules, cytokines, hematopoietic growth factors, acute phase proteins, transcription factors and viral genes.
An incomplete list of specific genes includes:
- amyloid precursor protein
- bcl-2
- bcl-X (bcl-xL)
- bcl-3
- cyclin D1
- fas ligand
- TNF-alpha
- interferon beta
- interferon gamma
- Ig kappa chain
- interleukin 2 receptor alpha
- interleukin 2
- interleukin 6
- interleukin 8
- interleukin 12 p40 subunit
- monocyte chemotactic protein-1
- c-myc
- c-myb
- SMAD-7
- cIAP1
- cIAP2
- XIAP
- TRAF1
- TRAF2
- NFkB1
- ICAM-1
- VCAM-1
- matrix metalloproteinase 9
- tissue plasminogen activator
- cyclooxygenase 2
- nitric oxide synthase 3
- tenascin-C
- gro-alpha (melanoma stimulatory factor)
General
nuclear factor kappa-B (NF-kappa B)