Neutra-Phos

Indications: phosphate replacement therapy Contraindications: pregnancy-category C safety in lactation ? Dosage: 1) 1 packet reconstituted with 75 mL of water 4 times/day 2) 1-2 tabs PO TID/QID 1 tab = 1 packet: 250 mg of phosphorous Contains equimolar amounts of Na⁺ & K⁺ phosphates Pharmacokinetics: elimination in urine Adverse effects: 1) mild laxative effect 2) headache 3) dizziness 4) confusion Drug interactions: 1) antacids: products containing aluminum, magnesium or calcium may bind phosphate & prevent absorption 2) calcium/vitamin D: the effects of phosphate may be antagonized in the treatment of hypocalcemia 3) K⁺ containing products: increased risk of hyperkalemia 4) K⁺ sparing diuretics: increased risk of hyperkalemia

General

urinary acidifier pharmacologic combination

References

Tarascon Pharmacopoeia, Tarascon Publishing, Loma Linda CA