Search
neuron navigator 1 (steerin-1, pore membrane &/or filament-interacting-like protein 3, Unc-53 homolog 1, unc53H1, NAV1, KIAA1151, KIAA1213, POMFIL3, STEERIN1)
Function:
- may be involved in neuronal migration (putative)
- interacts with tubulin (putative)
Structure: belongs to the Nav/unc-53 family
Compartment:
- cytoplasm, cytoskeleton (putative)
- associates with a subset of microtubule plus ends
- enriched in neuronal growth cones (putative)
Alternative splicing: named isoforms=7
Expression:
- broadly expressed at low levels
- expressed at high levels in heart, skeletal muscle & placenta
- expressed in fetal brain & heart
General
cytoskeletal protein
Properties
SIZE: MW = 202 kD
entity length = 1877 aa
COMPARTMENT: cytoplasm
MOTIF: coiled coil {255-280}
coiled coil {731-756}
coiled coil {1072-1163}
coiled coil {1303-1362}
Database Correlations
UniProt Q8NEY1
References
UniProt :accession Q8NEY1