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neuroglobin (NGB)
Function:
- role in oxygen transport in the brain
- monomer
Structure: belongs to the globin family
Expression:
- predominantly expressed in brain
- strongest expression in the frontal lobe, subthalamic nucleus & the thalamus
General
cytoskeletal protein
nuclear protein
Properties
SIZE: entity length = 151 aa
MW = 17 kD
COMPARTMENT: cell nucleus
MOTIF: Globin {1-149}
MOTIF: cysteine residue {C46}
MODIFICATION: cysteine residue {C55}
cysteine residue {C55}
MODIFICATION: cysteine residue {C46}
Iron [Fe]-binding site
SITE: 64-64
Iron [Fe]-binding site
SITE: 96-96
Database Correlations
OMIM 605304
UniProt Q9NPG2
Pfam PF00042
Entrez Gene 58157
Kegg hsa:58157
References
- UniProt :accession Q9NPG2
- Wikipedia; Note: neuroglobin entry
http://en.wikipedia.org/wiki/neuroglobin