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neurexophilin-4 (NXPH4, NPH4, UNQ1928/PRO4403)
Function:
- may be signaling molecules that resemble neuropeptides & that act by binding to alpha-neurexins & possibly other receptors
- may be proteolytically processed at the boundary between the N-terminal non-conserved & the central conserved domain in neuron-like cells
Structure: belongs to the neurexophilin family
Compartment: secreted (putative)
Expression: expressed in brain, spleen, & testis
General
neurexophilin
Properties
SIZE: entity length = 308 aa
MW = 33 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-23}
II {24-84}
MOTIF: N-glycosylation site {N72}
III {85-163}
MOTIF: N-glycosylation site {N133}
N-glycosylation site {N143}
N-glycosylation site {N149}
IV (linker domain) {164-224}
V (Cys-rich) {225-308}
Database Correlations
OMIM 604637
UniProt O95158
Entrez Gene 11247
Kegg hsa:11247
References
UniProt :accession O95158