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neurexophilin-2 (NXPH2 NPH2)
Function:
- may be signaling molecules that resemble neuropeptides & that act by binding to alpha-neurexins & possibly other receptors
- may be proteolytically processed at the boundary between the N-terminal non-conserved & the central conserved domain in neuron-like cells
Structure: belongs to the neurexophilin family
Compartment: secreted (putative)
Expression: expressed in brain & kidney
General
neurexophilin
Properties
SIZE: entity length = 264 aa
MW = 30 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-22}
II {23-90}
MOTIF: N-glycosylation site {N86}
III {91-169}
MOTIF: N-glycosylation site {N139}
N-glycosylation site {N149}
N-glycosylation site {N155}
IV (linker domain) {170-178}
V (Cys-rich) {179-264}
Database Correlations
OMIM 604635
UniProt O95156
Entrez Gene 11249
Kegg hsa:11249
References
UniProt :accession O95156