neuregulin

Of the four family members, neuregulins 1-4, most is known about neuregulin-1. Function: - ligands for receptor tyrosine kinases ErbB3 & ErbB4, leading to ErbB homodimers or heterodimers, often ErbB2

Specific

neuregulin-1; neu differentiation factor; heregulin; breast cancer cell differentiation factor p45; glial growth factor-2 (NRG1, GGF, HGL, HRG, HRGA, NDF, SMDF, ARIA) neuregulin-2, neural-& thymus-derived activator for ERBB kinases; divergent of neuregulin 1; DON-1 (NRG2, NTAK1) neuregulin-3 (NRG3) neuregulin-4; NRG-4 (NRG4)

General

growth factor secreted protein

Properties

COMPARTMENT: extracellular compartment