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neudesin (neuron-derived neurotrophic factor, secreted protein of unknown function, SPUF protein, NENF, SPUF)
Function:
- displays neurotrophic activity & activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 & AKT1/AKT in primary cultured neurons
- does not have mitogenic activity in primary cultured astrocytes
Structure: belongs to the cytochrome b5 family, MAPR subfamily
Compartment: secreted
General
secreted protein
Properties
SIZE: MW = 19 kD
entity length = 172 aa
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-31}
Database Correlations
UniProt Q9UMX5
Pfam PF00173
References
UniProt :accession Q9UMX5