netrin receptor

Receptors for netrins Function: 1) axon guidance 2) axon repulsion of neuronal growth cones in developing nervous system upon netrin binding 3) corticospinal tract axon guidance 4) apoptosis inhibited by netrin binding

Specific

deleted in colon cancer (DCC); netrin receptor DCC; tumor suppressor protein DCC; colorectal cancer suppressor; immunoglobulin superfamily DCC subclass member 1 (DCC, IGDCC1) UNC5 homolog protein

Properties

COMPARTMENT: plasma membrane MOTIF: ligand-binding site transmembrane domain

References

UniProt :accession O95185