NADH-cytochrome b5 reductase FLJ00377 (CYB5RL)

Function: - NADH-cytochrome b5 reductases are involved in desaturation & elongation of fatty acids, cholesterol - biosynthesis, drug metabolism, &, in erythrocyte, methemoglobin reduction (putative) NADH + 2 ferricytochrome b5 NAD⁺ + H⁺ + 2 ferrocytochrome b5 Cofactor: FAD (putative) Structure: - belongs to the flavoprotein pyridine nucleotide cytochrome reductase family Alternative splicing: named isoforms=3

General

flavoprotein oxidoreductase

Properties

SIZE: entity length = 314 aa MW = 36 kD MOTIF: cofactor-binding site [156-178] COFACTOR-BOUND: flavin adenine dinucleotide cofactor-binding site [181-213] COFACTOR-BOUND: flavin adenine dinucleotide

Database Correlations

UniProt Q6IPT4 Pfam PF00970 ENZYME 1.6.2.2

References

UniProt :accession Q6IPT4