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cadherin-15; muscle cadherin; M-cadherin; cadherin-14 (CDH15 CDH14 CDH3)
Function:
- cadherin
- M-cadherin is part of the myogenic program
- may provide a trigger for terminal muscle differentiation
Structure: contains 5 cadherin domains
Compartment: cell membrane
General
cadherin
glycoprotein
Properties
SIZE: entity length = 814 aa
MW = 89 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-21}
cadherin domain {61-152}
cadherin domain {153-260}
MOTIF: N-glycosylation site {N227}
cadherin domain {261-375}
cadherin domain {376-481}
cadherin domain {482-590}
MOTIF: N-glycosylation site {N531}
N-glycosylation site {N538}
N-glycosylation site {N576}
transmembrane domain {607-626}
Database Correlations
OMIM 114019
MORBIDMAP 114019
UniProt P55291
PFAM correlations
Entrez Gene 1013
Kegg hsa:1013
References
- UniProt :accession P55291
- Walsh FS et al
N-cadherin gene maps to human chromosome 18 and is not linked
to the E-cadherin gene.
J Neurochem. 1990 Sep;55(3):805-12.
PMID: 2384753