myotubularin-related protein 8 (MTMR8)

Function: - putative tyrosine-phosphatase - interacts with MTMR9 Structure: - belongs to the protein-tyrosine phosphatase family non-receptor class myotubularin subfamily - contains 1 myotubularin phosphatase domain Compartment: nucleus envelope Alternative splicing: named isoforms=2

General

nuclear protein tyrosine phosphatase (protein tyrosine phosphatate, PTP)

Properties

SIZE: entity length = 704 aa MW = 79 kD COMPARTMENT: cell nucleus MOTIF: Myotubularin phosphatase {126-500} MOTIF: Active site {338-344} cysteine residue {C338} coiled coil {515-541} STATE: active state

Database Correlations

UniProt Q96EF0 Pfam PF06602 Kegg hsa:5561

References

UniProt :accession Q96EF0