myotrophin; protein V-1 (MTPN)

Function: - potential role in cerebellar morphogenesis - may function in differentiation of cerebellar neurons, particularly granule cells - seems to be associated with cardiac hypertrophy Structure: - belongs to the myotrophin family - contains 3 ANK repeats Compartment: cytoplasm (putative) Expression: ubiquitous Genetics: - protein is produced by a bicistronic gene which also produces the MPD6 protein from a non-overlapping reading frame - MPD6 belongs to a group of cryptic antigens without conventional genomic structure - it is encoded by a cryptic open reading frame located in the 3'-untranslated region of MTPN

Properties

SIZE: entity length = 118 aa MW = 13 kD COMPARTMENT: cytoplasm MOTIF: ankyrin repeat NAME: ankyrin repeat SITE: 2-30 ankyrin repeat NAME: ankyrin repeat SITE: 34-66 ankyrin repeat NAME: ankyrin repeat SITE: 67-99

Database Correlations

OMIM 606484 UniProt P58546 Pfam PF00023 Entrez Gene 136319 Kegg hsa:136319

References

UniProt :accession P58546