myoneurin (zinc finger & BTB domain-containing protein 31, MYNN, OSZF, ZBTB31, SBBIZ1)

Structure: 1) belongs to the krueppel C2H2-type zinc-finger protein family 2) contains 1 BTB domain (POZ domain) - contains 8 C2H2-type zinc fingers Compartment: nucleus Alternative splicing: named isoforms=4 Expression: - expressed mainly in the neuromuscular system - located in & around synaptic myonuclei in adult muscle - also expressed in the testis, ovary & placenta Pathology: - expression is dysregulated after nerve injury

General

C2H2 type zinc finger protein nuclear protein

Properties

SIZE: MW = 69 kD entity length = 610 aa COMPARTMENT: cell nucleus MOTIF: BTB domain {24-89} MOTIF: Zinc finger NAME: Zinc finger EFFECTOR-BOUND: Zn+2 nuclear translocation signal {174-190} MOTIF: lysine-rich region {180-184} MOTIF: lysine residue (SEVERAL) nuclear translocation signal {257-262} Zn finger C2H2-type SITE: 302-324 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 330-352 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 358-381 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 387-409 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 415-437 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 443-465 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 471-493 EFFECTOR-BOUND: Zn+2 Zn finger C2H2-type SITE: 499-522 EFFECTOR-BOUND: Zn+2

Database Correlations

OMIM 606042 UniProt Q9NPC7 PFAM correlations

References

UniProt :accession Q9NPC7