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myoclonic dystonia; alcohol-responsive dystonia; dystonia-11

Movement disorder characterized by myoclonus & dystonia. Genetics: - autosomal dominant inheritance - associated with defects in DRD2 - associated with defects in SGCE (epsilon-sarcoglycan) Clinical manifestations: 1) involuntary jerks (myoclonus) 2) dystonia 3) alleviated by alcohol 4) age of onset & myoclonus, dystonia & response to alcohol is variable Management: see dystonia

General

genetic disease of muscle (inherited myopathy) dystonia myoclonus

Database Correlations

OMIM 159900

References

OMIM :accession 159900