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muscle aminopeptidase-N
present in liver
General
CD13; aminopeptidase-N; aminopeptidase-M; gp150; microsomal aminopeptidase; alanine aminopeptidase (ANPEP, PEPN)
molecular complex
Properties
SIZE: MW = 390 kD
COMPARTMENT: cytoplasm
cellular membrane
plasma membrane
CELL: monocyte
granulocyte
epithelial cell
hepatocyte
MOTIF: transmembrane domain {9-32}
Cytosolic Ser/Thr-rich junction {33-68}
Metalloprotease {69-967}
MOTIF: N-glycosylation site {N128}
N-glycosylation site {N234}
HCoV-229E interaction {260-353}
N-glycosylation site {N265}
N-glycosylation site {N319}
Zn+2-binding site
SITE: 388-388
glutamate residue {E389}
Zn+2-binding site
SITE: 392-392
Zn+2-binding site
SITE: 411-411
tyrosine residue {Y477}
N-glycosylation site {N527}
N-glycosylation site {N573}
N-glycosylation site {N625}
N-glycosylation site {N681}
N-glycosylation site {N735}
N-glycosylation site {N818}
Thr phosphorylation site {T928}
References
- Taylor A.
Aminopeptidases: structure and function.
FASEB J. 1993 Feb 1;7(2):290-8. Review.
PMID: 8440407