multimerin-2; EMILIN-3; elastin microfibril interface located protein 3; elastin microfibril interfacer 3; endoGlyx-1 p125/p140 subunit (MMRN2 EMILIN3)

Structure: - heteromer of p110, p125, p140 & p200 subunits - disulfide-linked - N- & O-glycosylated - contains 1 C1q domain - contains 1 EMI domain Compartment: - secreted, extracellular space, extracellular matrix Expression: endothelium

General

emilin; elastin microfibril interface located protein multimerin

Properties

SIZE: entity length = 949 aa MW = 104 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-22} EMI {54-132} MOTIF: cysteine residue {C58} MODIFICATION: cysteine residue {C122} cysteine residue {C85} MODIFICATION: cysteine residue {C92} cysteine residue {C92} MODIFICATION: cysteine residue {C85} cysteine residue {C121} MODIFICATION: cysteine residue {C130} cysteine residue {C122} MODIFICATION: cysteine residue {C58} cysteine residue {C130} MODIFICATION: cysteine residue {C121} coiled coil {167-187} N-glycosylation site {N205} N-glycosylation site {N214} N-glycosylation site {N249} N-glycosylation site {N261} coiled coil {292-487} MOTIF: N-glycosylation site {N350} N-glycosylation site {N379} N-glycosylation site {N439} N-glycosylation site {N472} coiled coil {547-596} coiled coil {688-711} N-glycosylation site {N727} N-glycosylation site {N765} lysine-rich region {779-806} MOTIF: lysine residue (SEVERAL) C1q {821-949} MOTIF: N-glycosylation site {N845}

Database Correlations

OMIM 608925 UniProt Q9H8L6 PFAM correlations Entrez Gene 79812 Kegg hsa:79812

References

UniProt :accession Q9H8L6