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multifunctional enzyme
Enzymes with at least 2 distinct catalytic activities
Specific
bifunctional aminoacyl-tRNA synthetase (prolyl tRNA synthetase, glutamyl tRNA synthetase, EPRS, GLNS, PARS, QARS, QPRS, PIG32)
fatty acid synthase; includes: [acyl-carrier-protein] S-acetyltransferase; [acyl-carrier-protein] S-malonyltransferase; 3-oxoacyl-[acyl-carrier-protein] synthase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase; enoyl-[acyl-carrier-protein] reductase; Oleoyl-[acyl-carrier-protein] hydrolase (FASN, FAS)
multifunctional protein ADE2; phosphoribosylaminoimidazole succinocarboxamide synthase; SAICAR synthetase; phosphoribosylaminoimidazole carboxylase (ADE2, AIRC, PAICS, PAIS)
patatin-like phospholipase domain-containing protein 3; acylglycerol O-acyltransferase; adiponutrin; Ca+2-independent phospholipase A2-epsilon; iPLA2-epsilon (PNPLA3, ADPN, C22orf20)
peroxisomal multifunctional enzyme type 2; MFE-2; 17-beta-hydroxysteroid dehydrogenase 4; 17-beta-HSD 4; D-bifunctional protein; DBP; multifunctional protein 2; MPF-2; contains: (3R)-hydroxyacyl-CoA dehydrogenase; enoyl-CoA hydratase 2; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase (HSD17B4, EDH17B4)
sialic acid synthase; N-acetylneuraminate synthase; N-acetylneuraminate-9-phosphate synthase; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase (NANS, SAS)
General
enzyme
Properties
MOTIF: active site