Search
Moyamoya disease
Epidemiology:
- rare
- higher incidence in Asians, particularly Japanese
Pathology:
- bilateral intracranial carotid artery occlusion
- ischemic stroke
- telangiectatic vessels in the region of the basal ganglia
Genetics:
- autosomal recessive
- two loci identified: chromosome 3p & chromosome 17q25
Clinical manifestations:
1) children
- hemiplegia, sudden onset
- epileptic seizures
2) adults
- subarachnoid bleeding
Interactions
disease interactions
General
cerebrovascular disease/disorder
genetic disease of blood vessels
genetic disease of the central nervous system
Database Correlations
OMIM correlations
LOCUS-LINK correlations
References
- National Institute of Neurological Disorders and Stroke (NINDS)
Moyamoya Disease Information Page
https://www.ninds.nih.gov/Disorders/All-Disorders/Moyamoya-Disease-Information-Page