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monocyte to macrophage differentiation protein (progestin & adipoQ receptor family member 11, MMD, PAQR11)
Function:
- involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion
Compartment: endosome, late endosomal membrane, lysosomal membrane
Expression:
- preferentially expressed in mature macrophages
Related
monocyte to macrophage differentiation factor 2 (progestin & adipoQ receptor family member X, MMD2, PAQR10)
General
progestin & adipoQ receptor (PAQR)
transmembrane 7 protein
Properties
SIZE: MW = 28 kD
entity length = 238 aa
COMPARTMENT: lysosome
endosome
MOTIF: transmembrane domain {29-49}
transmembrane domain {62-82}
transmembrane domain {102-122}
transmembrane domain {125-145}
transmembrane domain {152-172}
transmembrane domain {175-195}
transmembrane domain {199-219}
Database Correlations
OMIM 604467
UniProt Q15546
Pfam PF03006
References
UniProt :accession Q15546