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mixed lineage leukemia translocated to 6 (MLLT6, ALL1 fused gene from chromosome 17, AF17)
Pathology:
- a chromosomal translocation t(11;17)(q23;q21) involving MLLT6 with MLL/HRX is associated with acute leukemias
- the result is a rogue activator protein
Related
protein AF-17 (mixed lineage leukemia translocated to 6, MLLT6, ALL1 fused gene from chromosome 17 protein, AF17)
General
unclassified gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: protein AF-17
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
OMIM 600328
References
- UniProt :accession P55198
- Atlas of Genetics and Cytogenetics in Oncology and Haematology
http://atlasgeneticsoncology.org/Genes/AF17.html