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MLF1 gene; MLF1 myeloid leukemia factor 1 gene; myelodysplasia-myeloid leukemia factor 1 gene
Involved in chromosomal translocation t3q25:5q34 leading to NPM-MLF1 fusion protein, responsible for myelodysplastic syndrome (MDS) which progresses to acute myeloid leukemia (AML).
Related
chromosomal translocation t(3;5)(q25.1;q34)
myeloid leukemia factor 1; myelodysplasia-myeloid leukemia factor 1 (MLF1)
General
unclassified gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: myeloid leukemia factor 1
LOCUS: human chromosome-3 Q25
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
OMIM 601402
References
OMIM :accession 601402