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MKI67 FHA domain-interacting nucleolar phosphoprotein (nucleolar protein interacting with the FHA domain of pKI-67, hNIFK, nucleolar phosphoprotein Nopp34, MKI67IP, NIFK, NOPP34)
Function:
1) binds to the FHA domain of MKI67
2) interaction is enhanced in mitosis
3) phosphorylated
Compartment:
- nucleus, nucleolus
- localizes to mitotic chromosomes in conjunction with MKI67
General
nuclear protein
phosphoprotein
Properties
SIZE: MW = 34 kD
entity length = 293 aa
COMPARTMENT: cell nucleus
MOTIF: RNP motif
NAME: RNP motif
SITE: 45-123
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
NAME: ribonucleoprotein-1 motif
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
ribonucleoprotein-2 motif
ribonucleoprotein-2 motif
FOR-BINDING-OF: ribonucleic acid
MOTIF: ribonucleoprotein-1 motif
ribonucleoprotein-2 motif
binding site
SITE: 226-269
FOR-BINDING-OF: antigen KI-67
MOTIF: Thr phosphorylation site {T234}
Database Correlations
UniProt Q9BYG3
Pfam PF00076
References
UniProt :accession Q9BYG3