mixed cellular & humoral immune dysfunction

Etiology: 1) common variable hypogammaglobulinemia 2) ataxia telangiectasia 3) severe combined immunodeficiency 4) Wiskott-Aldrich syndrome 5) diabetes mellitus 6) hyper IgE syndrome (Job's syndrome) Pathology: Pathogens: 1) common variable hypogammaglobulinemia a) Pneumocystis carinii b) cytomegalovirus c) Streptococcus pneumoniae d) Haemophilus influenzae e) other bacteria 2) ataxia telangiectasia a) Streptococcus pneumoniae b) Haemophilus influenzae c) Staphylococcus aureus d) rubella virus e) Giardia lamblia 3) severe combined immunodeficiency a) Streptococcus pneumoniae b) Haemophilus influenzae c) Staphylococcus aureus d) Candida albicans e) Pneumocystis carinii f) varicella-zoster virus g) rubella virus h) cytomegalovirus 4) Wiskott-Aldrich syndrome -> agents seen in cellular & humoral immune dysfunction

Related

cellular immune dysfunction humoral immune dysfunction

Specific

combined immune deficiency; severe combined immunodeficiency disease (SCID CID) common variable immunodeficiency (CVID) hyperimmunoglobulin E (Job's syndrome) immune dysfunction in diabetes mellitus Wiskott-Aldrich syndrome (eczema-thrombocytopenia-immunodeficiency syndrome)

References

Harrison's Principles of Internal Medicine, 13th ed. Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 497