mitochondrial inner membrane protease

Function: 1) catalyzes removal of transit peptides required for targeting of proteins from the mitochondrial matrix, across the mitochondrial inner membrane, into the inter-membrane space 2) processes nuclear encoded protein DIABLO Structure: - heterodimer of 2 subunits, IMMP1L & IMMP2L Comaprtment: mitochondrial inner membrane Expression: expressed in all tissues tested except adult liver & lung

General

mitochondrial membrane protein molecular complex protease; proteinase; endopeptidase

Properties

COMPARTMENT: mitochondrial membrane MOTIF: active site membrane region SUBUNITS: mitochondrial inner membrane protease subunit 1 COMPARTMENT: mitochondria MOTIF: serine residue {S40} lysine residue {K83} mitochondrial inner membrane protease subunit 2 COMPARTMENT: mitochondria MOTIF: transmembrane domain {19-37} serine residue {S43} lysine residue {K91}

References

UniProt :accession Q96T52

Components

mitochondrial inner membrane protease subunit 1 (IMP1-like protein, IMMP1L) mitochondrial inner membrane protease subunit 2 (IMP2-like protein, IMMP2L)