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metanephrines in urine
Indications:
- screening test of choice for pheochromocytoma
Normal range:
- see metanephrines in 24 hour urine
Increases:
- catecholamine-secreting neurochromaffin tumors
- pheochromocytoma
- paraganglioma
- neuroblastome
- pharmaceutical agents:
a) in vivo effects
- nitroglycerin, phenothiazines
b) chemical interferences
- vitamin B (high doses), erythromycin, hydralazine, levodopa, methenamine hippurate, methenamine mandelate, methyldopa, nicotinic acid, quinine, quinidine, salicylate, tetracyclines
Decreases:
- pharmaceutical agents:
- in vivo effects
- MAO inhibitors
Interferences:
1) sympathomimetics
2) tricyclic antidepressants
3) labetalol [1]
Related
metanephrine
pheochromocytoma; paroxysmal hypertension; adrenal medullary paraganglioma; chromoffinoma
Specific
metanephrines in 24 hour urine
General
urine chemistry test
References
- Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed)
Lippincott-Raven, Philadelphia, 1998, pg 483
- Clinical Diagnosis & Management by Laboratory Methods,
19th edition, J.B. Henry (ed), W.B. Saunders Co.,
Philadelphia, PA. 1996, pg 12
- Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed,
WB Saunders, Philadelphia, 2006
- Panel of 12 tests
Laboratory Test Directory ARUP: 80436
Component-of
metanephrines/creatinine in urine