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metal transporter CNNM4 (Cyclin-M4, Ancient conserved domain-containing protein 4, CNNM4, ACDP4, KIAA1592)
Function:
- probable metal transporter
- interaction with the metal ion chaperone COX11 suggests a role in sensory neuron functions (putative)
- interacts with COX11
Structure:
- belongs to the ACDP family
- contains 1 CBS domain
- shares weak sequence similarity with the cyclin family, explaining its name; however it has no cyclin-like function in vivo
Compartment: cell membrane
Expression:
- widely expressed
- highly expressed in heart
Note: Shares weak sequence similarity with the cyclin family, explaining its name. However it has no cyclin-like function in vivo
General
carrier protein (transporter)
glycoprotein
membrane protein
Properties
SIZE: entity length = 775 aa
MW = 87 kD
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {19-39}
N-glycosylation site {N85}
N-glycosylation site {N122}
transmembrane domain {179-199}
transmembrane domain {241-261}
transmembrane domain {265-285}
transmembrane domain {294-316}
CBS {397-504}
Database Correlations
OMIM 607805
MORBIDMAP 607805
UniProt Q6P4Q7
PFAM correlations
Entrez Gene 26504
References
UniProt :accession Q6P4Q7