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metal in urine

Pathology: - metals in urine associated with risk of cardiovascular disease (CVD) & death* Metal RR of CVD RR of death cadmium 1.25 1.68 copper 1.42 1.50 zinc 1.21 1.38 cobalt 1.24 1.37 uranium 1.32 1.32 tungsten 1.20 1.16 * cadmium, copper, zinc cobalt, uranium, tungsten - these same metals are associated with coronary artery calcium [2]

General

urine chemistry test

References

  1. Lou N These Metals in Urine Predict Heart Disease and Death. Exposure may come from food, water, and air MedPage Today, August 1, 2024 https://www.medpagetoday.com/cardiology/prevention/111319 - Martinez-Morata I, Schilling K, Glabonjat RA et al Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2024. August 1. PMID: 39087344 https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.124.069414
  2. McGraw KE, Schilling K, Glabonjat RA et al Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis (MESA). medRxiv [Preprint]. 2023 Nov 1:2023.10.31.23297878. PMID: 37961623 PMCID: PMC10635251 Free PMC article. Preprint. - McGraw KE, Schilling K, Glabonjat RA et al Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis. J Am Coll Cardiol. 2024 Sep 12:S0735-1097(24)07961-0 PMID: 39297845 Free article. https://www.jacc.org/doi/10.1016/j.jacc.2024.07.020