mesogenin-1 (MSGN1)

Function: - role in the formation & segmentation of paraxial mesoderm - regulatory capacity to specify ventrolateral (including future paraxial), but not dorsal (future axial), mesoderm phenotypes - seems to be an upstream regulator of at least some elements of the notch & delta signaling pathway Structure: contains 1 basic helix-loop-helix (bHLH) domain Compartment: nucleus (putative)

Properties

SIZE: entity length = 193 aa MW = 21 kD COMPARTMENT: cell nucleus MOTIF: DNA-binding motif SITE: 124-136 helix-loop-helix NAME: helix-loop-helix SITE: 137-179 FOR-BINDING-VIA: helix-loop-helix

Database Correlations

UniProt A6NI15 Pfam PF00010 Kegg hsa:3439

References

UniProt :accession A6NI15