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mesoderm posterior protein 1 (MESP1)
Function:
- transcription factor
- role in epithelialization of somitic mesoderm & in development of cardiac mesoderm
- defines the rostrocaudal patterning of somites by participating in distinct Notch pathways
Structure:
- contains 1 basic helix-loop-helix (bHLH) domain
- N- & C-terminal domains are separated by a 2-repeat G-Q region
Compartment: nucleus (probable)
General
basic helix loop helix (bHLH) family transcription factor
Properties
SIZE: entity length = 268 aa
MW = 29 kD
COMPARTMENT: cell nucleus
MOTIF: DNA-binding motif
SITE: 75-90
helix-loop-helix
NAME: helix-loop-helix
SITE: 91-137
FOR-BINDING-VIA: helix-loop-helix
basic helix-loop-helix
MOTIF: basic DNA-binding motif
helix-loop-helix
NAME: helix-loop-helix
FOR-BINDING-VIA: helix-loop-helix
FOR-BINDING-OF: DNA motif
FOR-BINDING-VIA: helix-loop-helix
CPLCP {163-167}
repeats {182-185}
MOTIF: consensus repeat {182-183}
consensus repeat {184-185}
Database Correlations
OMIM 608689
UniProt Q9BRJ9
Pfam PF00010
References
UniProt :accession Q9BRJ9