melanoma inhibitory activity protein 2 (MIA2)

Structure: - belongs to the MIA/OTOR family - contains 1 SH3 domain Compartment: secreted Alternative splicing: named isoforms=2 Expression: - expressed in live > testis Pathology: - role in the pathophysiology of liver disease - may serve as a marker of liver damage - expression higher in patients with severe cirrhosis or inflammation & chronic hepatitis

Related

melanoma melanoma-derived growth regulatory protein; melanoma inhibitory activity protein (MIA)

General

glycoprotein secreted protein

Properties

SIZE: MW = 62 kD entity length = 541 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-22} src homology 3 [SH3] domain SITE: 23-117 MOTIF: N-glycosylation site {N59} N-glycosylation site {N367}

Database Correlations

OMIM 608001 UniProt Q96PC5 Pfam PF07653

References

UniProt :accession Q96PC5