Search
melanoma-associated antigen 4; MAGE-4 antigen; MAGE-X2 antigen; MAGE-41 antigen; cancer/testis antigen 1.4; CT1.4 (MAGEA4, MAGE4)
Function:
- unknown
- may play a role in embryonal development, tumor transformation or aspects of tumor progression
Structure: contains 1 MAGE domain
Expression:
- expressed in many tumors of several types, including melanoma, head & neck squamous cell carcinoma, lung carcinoma & breast carcinoma
- not expressed in normal tissues except testes & placenta
Laboratory:
- MAGE A4 Ab in serum/plasma
General
melanoma associated antigen (MAGE)
Properties
SIZE: entity length = 317 aa
MW = 35 kD
MOTIF: serine-rich region {41-44}
MOTIF: serine residue (SEVERAL)
melanoma-associated antigen (MAGE) domain {110-309}
Database Correlations
OMIM 300175
UniProt P43358
Pfam PF01454
Entrez Gene 4103
Kegg hsa:4103
References
- UniProt :accession P43358
- Entrez Gene :accession 4103