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Meiotic nuclear division protein 1 homolog (MND1 GAJ)
Function:
- required for proper homologous chromosome pairing & efficient cross-over & intragenic recombination during meiosis (putative)
- stimulates both DMC1- & RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks
- heterodimer with PSMC3IP/HOP2
- MND1-PSMC3IP interacts with DMC1 & RAD51 & binds preferentially to dsDNA
Structure: belongs to the MND1 family
Compartment: nucleus (probable)
General
DNA-binding protein
Properties
SIZE: entity length = 205 aa
MW = 24 kD
COMPARTMENT: cell nucleus
MOTIF: coiled coil {84-173}
Database Correlations
UniProt Q9BWT6
Pfam PF03962
Kegg hsa:8405
References
UniProt :accession Q9BWT6