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medical conditions associated with constipation

Etiology: 1) mechanical obstruction a) colon cancer b) external compression from malignancy c) stricture (diverticulosis ischemia) d) rectocele (large) e) postsurgical anomalies f) megacolon g) anal fissure 2) metabolic disorders, endocrine disorders a) diabetes mellitus b) hypothyroidism c) hypercalcemia d) hypokalemia e) hypomagnesemia f) uremia g) pregnancy h) porphyria i) panhypopituitarism j) anorexia k) heavy metal poisoning 3) myopathies & connective tissue disorders a) amyloidosis b) scleroderma c) dermatomyositis d) myotonic dystrophy 4) neuropathies a) Parkinson's disease b) spinal cord injury or tumor c) cerebrovascular disease d) multiple sclerosis e) autonomic neuropathy f) Hirshsprung disease g) Chagas disease h) neurofibromatosis i) ganglioneuromatosis j) intestinal pseudo-obstruction (myopathy, neuropathy) 5) other conditions a) depression b) cognitive impairment c) immobility d) cardiac disease

References

  1. Locke GR et al AGA technical review on constipation. American Gastroenterological Association. Gastroenterology 119:1766, 2000 PMID: 11113099
  2. Medical Knowledge Self Assessment Program (MKSAP) 15, 16, 17. American College of Physicians, Philadelphia 2009, 2012, 2015