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mechanic's hands

Etiology: - dermatomyositis - anti-synthetase syndrome [2,3] - myositis - Raynaud's syndrome - interstitial lung disease with anti-Jo-1 Ab Clinical manifestations: - scaley, rough, dry, hyperkeratotic fissured skin with cracked horizontal lines on palmar & lateral aspects of the fingers - described as 'thickened skin on tips & margins' of fingers (NEJM) [4]

General

sign/symptom

References

  1. Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015 - Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022
  2. Chatterjee S, Prayson R, Fraver C. Antisynthetase syndrome: Not just an inflammatory myopathy. Cleveland Clinic Journal of Medicine 2013;80:655-666. PMID: 24085811
  3. Chatterjee S Mechanic's Hands N Engl J Med 2021; 384:e16. Feb 11 PMID: 33567195 https://www.nejm.org/doi/full/10.1056/NEJMicm2026773
  4. NEJM Knowledge+'thi