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May-Hegglin anomaly
Genetics:
- autosomal dominant
- associated with defects in MYH9
Clinical manifestations:
- asymptomatic
Laboratory:
- complete blood count may show thrombocytopenia
- peripheral blood smear:
a) giant platelets
b) leukokyte inclusions appearing as highly parallel paracrystalline bodies (Dohle bodies)
General
congenital anomaly (birth defect)
genetic disease of the blood/bone marrow
Database Correlations
OMIM 155100
References
- Williams Hematology, 5th ed, E Beutler, MA Lichtman,
BS Coller & TJ Kipps (eds), McGraw Hill, NY, 1995, pg 1282
- OMIM :accession 155100