Search
matrix-remodelling-associated protein 5 (adhesion protein with leucine-rich repeats & immunoglobulin domains related to perlecan, adlican, MXRA5)
Structure:
- contains 12 Ig-like C2-type domains (immunoglobulin-like) contains 7 LRR repeats (leucine-rich repeats)
Compartment: secreted
Expression:
- over-expressed in centenarians
- expression is diminished from young to old but increased from old to centenarians
General
adhesion protein
glycoprotein
matrix protein
Properties
SIZE: MW = 312 kD
entity length = 2828 aa
COMPARTMENT: extracellular matrix
MOTIF: signal sequence {1-26}
leucine-rich repeat
SITE: 54-77
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 78-101
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 103-125
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 126-149
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 151-173
MOTIF: leucine residue (SEVERAL)
leucine-rich repeat
SITE: 182-205
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N287}
N-glycosylation site {N321}
immunoglobulin superfamily domain {481-571}
MOTIF: cysteine residue {C501}
MODIFICATION: cysteine residue {C555}
cysteine residue {C555}
MODIFICATION: cysteine residue {C501}
immunoglobulin superfamily domain {575-669}
MOTIF: cysteine residue {C599}
MODIFICATION: cysteine residue {C651}
N-glycosylation site {N633}
cysteine residue {C651}
MODIFICATION: cysteine residue {C599}
N-glycosylation site {N1403}
leucine-rich repeat
SITE: 1410-1434
MOTIF: leucine residue (SEVERAL)
N-glycosylation site {N1735}
immunoglobulin superfamily domain {1853-1946}
MOTIF: cysteine residue {C1875}
MODIFICATION: cysteine residue {C1928}
cysteine residue {C1928}
MODIFICATION: cysteine residue {C1875}
immunoglobulin superfamily domain {1950-2041}
MOTIF: cysteine residue {C1972}
MODIFICATION: cysteine residue {C2025}
N-glycosylation site {N2007}
cysteine residue {C2025}
MODIFICATION: cysteine residue {C1972}
immunoglobulin superfamily domain {2046-2140}
MOTIF: N-glycosylation site {N2056}
cysteine residue {C2069}
MODIFICATION: cysteine residue {C2122}
cysteine residue {C2122}
MODIFICATION: cysteine residue {C2069}
immunoglobulin superfamily domain {2146-2239}
MOTIF: cysteine residue {C2168}
MODIFICATION: cysteine residue {C2221}
cysteine residue {C2221}
MODIFICATION: cysteine residue {C2168}
immunoglobulin superfamily domain {2242-2343}
MOTIF: cysteine residue {C2265}
MODIFICATION: cysteine residue {C2324}
cysteine residue {C2324}
MODIFICATION: cysteine residue {C2265}
immunoglobulin superfamily domain {2345-2432}
MOTIF: cysteine residue {C2368}
MODIFICATION: cysteine residue {C2418}
cysteine residue {C2418}
MODIFICATION: cysteine residue {C2368}
immunoglobulin superfamily domain {2440-2534}
MOTIF: cysteine residue {C2466}
MODIFICATION: cysteine residue {C2518}
cysteine residue {C2518}
MODIFICATION: cysteine residue {C2466}
immunoglobulin superfamily domain {2542-2630}
MOTIF: cysteine residue {C2564}
MODIFICATION: cysteine residue {C2616}
cysteine residue {C2616}
MODIFICATION: cysteine residue {C2564}
immunoglobulin superfamily domain {2637-2722}
MOTIF: cysteine residue {C2659}
MODIFICATION: cysteine residue {C2711}
N-glycosylation site {N2693}
cysteine residue {C2711}
MODIFICATION: cysteine residue {C2659}
immunoglobulin superfamily domain {2733-2828}
MOTIF: cysteine residue {C2755}
MODIFICATION: cysteine residue {C2810}
cysteine residue {C2810}
MODIFICATION: cysteine residue {C2755}
Database Correlations
UniProt Q9NR99
PFAM correlations
References
UniProt :accession Q9NR99