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Majeed syndrome

Genetics: - autosomal recessive - associated with defects in LPIN2 Clinical manifestations: 1) chronic recurrent multifocal osteomyelitis with early onset & lifelong course 2) congenital dyserythropoietic anemia presenting as hypochromic, microcytic anemia during the first year of life, ranging from mild to transfusion-dependent 3) transient inflammatory dermatosis, often manifesting as Sweet syndrome (neutrophilic skin infiltration)

General

genetic syndrome (multisystem disorder)

Database Correlations

OMIM 609628

References

UniProt :accession Q92539