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MAGUK p55 subfamily member 3; membrane protein palmitoylated 3; MPP3 protein; discs large homolog 3 (MPP3, DLG3)
Function:
- interacts with HTR2A (putative)
- interacts (via PDZ domain) with CADM1 (via C-terminus)
- interacts with HTR4
Structure:
- belongs to the MAGUK family
- contains 1 guanylate kinase-like domain
- contains 2 L27 domains
- contains 1 PDZ domain (DHR domain)
- contains 1 SH3 domain
Related
discs large homolog
disks large-associated protein 1; DAP-1; guanylate kinase-associated protein; hGKAP; SAP90/PSD-95-associated protein 1; SAPAP1; PSD-95/SAP90-binding protein 1 (DLGAP1 DAP1 GKAP)
drosophila discs large [dlg] protein
General
cytoskeletal protein
MAGUK p55 subfamily
Properties
SIZE: MW = 66 kD
entity length = 585 aa
COMPARTMENT: cytoplasm
MOTIF: L27-1 {6-60}
L27-2 {61-118}
PDZ domain
NAME: PDZ domain
SITE: 137-212
src homology 3 [SH3] domain
SITE: 226-296
domain {385-570}
HOMOLOGY: guanylate kinase
Database Correlations
OMIM 601114
UniProt Q13368
PFAM correlations
Entrez Gene 4356
Kegg hsa:4356
References
UniProt :accession Q13368