magnesium gluconate (Magonate)

Tradename: Magonate. Indication: treatment of magnesium deficiency Contraindication: pregnancy-category :value A safety-in-lactation :value + Dosage: 1) 27-54 mg BID-TID 2) 100 mg QID 3) dosage adjustment &/or monitoring necessary in patients with renal failure Pharmacokinetics: 1) 15 to 30% absorbed following oral administration 2) elimination :route kidney) Adverse effects: 1) diarrhea 2) hypotension 3) abdominal cramps 4) muscle weakness 5) respiratory depression Drug interactions: - may increase effects of non-depolarizing neuromuscular junction blockers Mechanism of action: cofactor in enzymatic reactions

References

Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998 Department of Veterans Affairs, VA National Formulary