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magic mouthwash

a term encompassing ~50 varieties of lidocaine-based mouth rinses Indications: - widely used for oral mucositis pain * diphenhydramine/lidocaine/antacid preparation used at Mayo Clinic is effective in reducing radiotherapy-associated oral mucositis pain Adverse effects: - oral numbness & loss of taste [2] Notes: - may not be covered by insurance [2]

Interactions

drug interactions

General

topical agent

References

  1. Mulcahy N Magic Mouthwash Really Works, Says Phase 3 Trial. Medscape. Sep 27, 2016. http://www.medscape.com/viewarticle/869314
  2. Uberoi AS, Brown TJ, Gupta A. Magic Mouthwash for Oral Mucositis. A Teachable Moment. JAMA Intern Med. 2019;179(1):104-105. PMID: 30453313 https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2715162

Components

antacid diphenhydramine (Benadryl, Alledryl, Allergival) lidocaine (Xylocaine)