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Maestro heat-like repeat-containing protein family member 7; HEAT repeat-containing protein 8 (MROH7, C1orf175, HEATR8)
Structure: contains 4 HEAT repeats
Compartment: membrane (putative)
Alternative splicing:
- named isoforms=6
- at least one isoform may be expressed at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay
General
glycoprotein
HEAT repeat-containing protein (HEATR)
membrane protein
Properties
SIZE: entity length = 1323 aa
MW = 146 kD
COMPARTMENT: cellular membrane
MOTIF: serine-rich region {252-355}
MOTIF: serine residue (SEVERAL)
N-glycosylation site {N318}
N-glycosylation site {N438}
N-glycosylation site {N586}
transmembrane domain {593-613}
transmembrane domain {767-787}
HEAT repeat {957-995}
HEAT repeat {1036-1074}
HEAT repeat {1079-1117}
HEAT repeat {1125-1162}
Database Correlations
UniProt Q68CQ1
Entrez Gene 374977
Kegg hsa:374977
References
UniProt :accession Q68CQ1