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mitotic spindle assembly checkpoint protein MAD2B; mitotic arrest deficient 2-like protein 2; MAD2-like protein 2; REV7 homolog; hREV7 (MAD2L2, MAD2B, REV7)
Function:
- binds REV1L (putative)
- interacts with REV3 & with ADAM9 (MDC9) & ADAM15; weakly with ADAM19 & not with ADAM17
- component_of DNA polymerase zeta
Structure: contains 1 HORMA domain
General
nuclear protein
protein subunit
Properties
SIZE: entity length = 211 aa
MW = 24 kD
COMPARTMENT: cell nucleus
MOTIF: HORMA {13-203}
Database Correlations
OMIM 604094
UniProt Q9UI95
Pfam PF02301
Entrez Gene 10459
Kegg hsa:10459
References
- UniProt :accession Q9UI95
- NIEHS-SNPs
http://egp.gs.washington.edu/data/mad2l2/
Component-of
DNA polymerase zeta