macrophage-stimulating protein MSTP9; brain rescue factor 1; BRF-1; hepatocyte growth factor-like protein homolog (MSTP9, MST1P9, D1F15S1A, MST1L)

Function: - probably has no proteolytic activity, since serine protease catalytic site insufficiently conserved Structure: - belongs to the peptidase S1 family, plasminogen subfamily - contains 4 kringle domains - contains 1 PAN domain - contains 1 peptidase S1 domain Compartment: secreted (putative) Alternative splicing: named isoforms=2 Note: could be the product of a pseudogene

Properties

SIZE: entity length = 715 aa MW = 80 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-20} PAN {21-110} Kringle 1 {63-156} MOTIF: cysteine residue {C127} MODIFICATION: cysteine residue {C151} cysteine residue {C151} MODIFICATION: cysteine residue {C127} Kringle 2 {160-238} MOTIF: cysteine residue {C161} MODIFICATION: cysteine residue {C238} cysteine residue {C182} MODIFICATION: cysteine residue {C221} cysteine residue {C210} MODIFICATION: cysteine residue {C233} cysteine residue {C221} MODIFICATION: cysteine residue {C182} cysteine residue {C233} MODIFICATION: cysteine residue {C210} cysteine residue {C238} MODIFICATION: cysteine residue {C161} Kringle 3 {252-345} MOTIF: cysteine residue {C253} MODIFICATION: cysteine residue {C345} cysteine residue {C316} MODIFICATION: cysteine residue {C339} cysteine residue {C339} MODIFICATION: cysteine residue {C316} cysteine residue {C345} MODIFICATION: cysteine residue {C253} Kringle 4 {353-464} MOTIF: cysteine residue {C354} MODIFICATION: cysteine residue {C464} cysteine residue {C375} MODIFICATION: cysteine residue {C447} cysteine residue {C447} MODIFICATION: cysteine residue {C375} cysteine residue {C464} MODIFICATION: cysteine residue {C354} S1 domain {488-713} MOTIF: cysteine residue {C511} MODIFICATION: cysteine residue {C527} cysteine residue {C527} MODIFICATION: cysteine residue {C511} cysteine residue {C606} MODIFICATION: cysteine residue {C671} cysteine residue {C636} MODIFICATION: cysteine residue {C650} cysteine residue {C650} MODIFICATION: cysteine residue {C636} cysteine residue {C661} MODIFICATION: cysteine residue {C689} cysteine residue {C671} MODIFICATION: cysteine residue {C606} cysteine residue {C689} MODIFICATION: cysteine residue {C661}

Database Correlations

UniProt Q2TV78 PFAM correlations

References

UniProt :accession Q2TV78