L-myc proto-oncogene protein

The supertype PEST protein was included for consisitency with c-myc protein & no other reason.

Specific

L-myc-1 proto-oncogene protein (MYCL1, LMYC, MYCL) myc-like protein MYCLP1; protein L-Myc-2; V-myc myelocytomatosis viral oncogene homolog pseudogene 1 (MYCLP1, MYCL1P1, MYCL2)

General

myc protein family PEST protein proto oncogene protein

Properties

COMPARTMENT: cell nucleus MOTIF: basic helix-loop-helix {BHLH} MOTIF: basic DNA-binding motif helix-loop-helix NAME: helix-loop-helix FOR-BINDING-VIA: helix-loop-helix FOR-BINDING-OF: DNA motif FOR-BINDING-VIA: helix-loop-helix leucine zipper SITE: LZ FOR-BINDING-VIA: leucine zipper S/T phosphorylation site transcriptional activation domain MOTIF: binding site FOR-BINDING-OF: general transcription factor II-I

References

- Dwarki VJ, Montminy M, Verma IM. Both the basic region and the 'leucine zipper' domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. EMBO J. 1990 Jan;9(1):225-32. PMID: 2136830