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Lyme (Borrelia burgdorferi) vaccine (Lymerix, OspA protein)

Indications: -> prevention of Lyme disease Off the market in 2002 due to low demand. Dosage: 1) doses at 0, 1 & 2-6 months 2) booster at 12 months & yearly therafter Pharmacokinetics: 1) 50% effective after 2nd dose 2) 78% effective after 3rd dose Adverse effects: 1) arthritis 2) muscle pain Mechanism of action: 1) stimulation of antibody production that work in the gut of the offending tick 2) contains synthetic form of OspA protein

General

vaccine

References

  1. Prescriber's Letter 7(2):7, Feb. 2000
  2. Prescriber's Letter 8(3):14 2001
  3. Prescriber's Letter 9(4):21 2002
  4. RxList http://www.rxlist.com/lymerix-drug.htm