lyase

Function: - enzyme capable of catalyzing the cleavage of C-C, C-O, or C-N bonds by elimination - a double bond is formed in these reactions

Specific

2-hydroxyacyl-CoA lyase 1; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; phytanoyl-CoA 2-hydroxylase 2 (HACL1, HPCL, HPCL2, PHYH2, HSPC279) adenyl cyclase, adenylyl cyclase or adenylate cyclase adenylosuccinate lyase (adenylosuccinase, ADSL, ASASE, AMPS, ASL) aldehyde lyase (aldolase) ammonia lyase argininosuccinate lyase (argininosuccinase, ASAL, ASL) carboxy-lyase or decarboxylase cystathionine gamma-lyase (gamma-cystathionase, CTH) cytochrome C heme lyase; holocytochrome c synthase (HCCS, CCHL) cytochrome C1 heme lyase dihydrodipicolinate synthase-like, mitochondrial; DHDPS-like protein (HOGA1, C10orf65) DNA photolyase DNA-(apurinic or apyrimidinic site) lyase 2; AP endonuclease XTH2; APEX nuclease 2; APEX nuclease-like 2; apurinic-apyrimidinic endonuclease 2; AP endonuclease 2 (APEX2, APE2, APEXL2, XTH2) Endonuclease 8-like 1 (Nei-like 1, DNA glycosylase/AP lyase Neil1, DNA-[apurinic or apyrimidinic site] lyase Neil1, NEH1, FPG1, NEIL1) endonuclease 8-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; endonuclease VIII-like 2; Nei homolog 2; NEH2; Nei-like protein 2 (NEIL2) ferrochelatase, mitochondrial; heme synthase; protoheme ferro-lyase (FECH) guanyl cyclase or guanylate cyclase hyaluronoglucosaminidase; hyaluronidase (HYAL) hydro-lyase, hydratase or dehydratase ketoacid-lyase Kynurenine--oxoglutarate transaminase 3 (kynurenine aminotransferase 3, KAT3, cysteine-S-conjugate beta-lyase 2, CCBL2, KAT3, RBMXL1) L-serine dehydratase; L-serine deaminase (SDS, SDH) lactoylglutathione lyase; methylglyoxalase; aldoketomutase; glyoxalase I; Glx I; ketone-aldehyde mutase; S-D-lactoylglutathione methylglyoxal lyase (GLO1) leukotriene C4 synthase; LTC4 synthase; leukotriene-C(4) synthase (LTC4S) molybdenum cofactor sulfurase (MoCo sulfurase, MOS, HMCS, MOCOS) photolyase Selenocysteine lyase (hSCL, SCLY, SCL) serine dehydratase-like (serine dehydratase 2, SDSL) sphingosine-1-phosphate lyase 1 (SP-lyase, hSPL, sphingosine-1-phosphate aldolase, SGPL1, KIAA1252) Threonine synthase-like 2 (TSH2, THNSL2) urocanate hydratase (urocanase, imidazolonepropionate hydrolase, UROC1)

Properties

MOTIF: active site

References

Stryer Biochemistry WH Freeman & Co, New York, 1988 pg 488